Meet The Worlds First HydrogenElectric Passenger Aircraft Element One

Watch This BlackFly Electric VTOL Aircraft In Flight This Electric Aircraft Features A 900-kWh Battery, 650-Mile Range Range – depending on whether hydrogen is stored in gaseous or liquid form – is to be from 500 km (310 miles) to 5,000 km (3,100 miles). Refueling will take some 10 minutes.HES Energy Systems said that it worked on the project for 12 years and intends to build the first flying prototype before 2025, which means another 7 years. We will not even guess how many more years will be needed to launch production and sales. Here is the world’s first regional hydrogen-electric passenger aircraft concept.It’s been quite some time since the LZ 129 Hindenburg and it seems that there is a new wave of daredevils that would like to make hydrogen fly again.The new approach is, of course, not to use the hydrogen element (the lightest element) to lift the aircraft up, but to make electricity in fuel cells, for electric motors that propel the…umm…propellers.Singapore’s HES Energy Systems presents the Element One, the world’s first regional hydrogen-electric passenger aircraft. The ultra-light Element One can take up to four passengers and is envisioned for fully autonomous flying.See Also 4 photos Source: Electric Vehicle News Author Liberty Access TechnologiesPosted on October 3, 2018Categories Electric Vehicle News Norway Eyes Electric Aircraft As Next Form Of Electric Transport Press blast:Singapore’s HES Unveils Plans for Regional Hydrogen-Electric Passenger Aircraft.Singapore, Paris – October 2nd, 2018  After 12 years developing hydrogen propulsion systems for small unmanned aircraft, HES Energy Systems is today unveiling its plans for Element One, the world’s first regional hydrogen-electric passenger aircraft.One century after the start of commercial aviation, HES is joining forces with a variety of partners to pioneer a new form of aerial mobility: quiet and zero carbon, personalized, on-demand, decentralized and economically inclusive of rural communities.Designed as a zero-emissions aircraft, Element One merges HES’ ultra-light hydrogen fuel cell technologies with a distributed electric aircraft propulsion design. With virtually no change to its current drone-scale systems, HES’ distributed system allows for modularity and increased safety through multiple system redundancies.Element One is designed to fly 4 passengers for 500 km to 5000 km depending on whether hydrogen is stored in gaseous or liquid form. This performance is several orders of magnitude better than any battery-electric aircraft attempt so far, opening new aerial routes between smaller towns and rural areas using an existing and dense network of small-scale airports and aerodromes.Originally from Singapore, HES has been working with a number of fast-moving start-ups and SMEs in France over the past year and exploring various locations to execute its Element One vision, including Aerospace Valley, the global aviation R&D hub located in Toulouse. Its parent company H3 Dynamics has been a symbol of intensifying technological cooperation between the two countries as part of the 2018 Year of Innovation.The promise of hydrogen-electric power could shape the future of aviation. “It’s now possible to break past the endurance limits of battery-electric flight using HES’ ultra-light hydrogen energy storage in a distributed propulsion arrangement” says Taras Wankewycz, founder of HES. “Element One’s design paves the way for renewable hydrogen as a long-range fuel for electric aviation.”Refueling Element One will take no more than 10 minutes using an automated nacelle swap system that applies AGVs and automated warehouse operations such as those used by Amazon and Alibaba.Last week, HES announced its plans to begin associating on-site hydrogen generation with fuel cell powered unmanned aircraft across a network of hydrogen-ready airports, in preparation for larger-scale electric aircraft such as Element One. HES is now in discussion with industrial-scale hydrogen producers to explore energy-efficient refueling systems using renewable solar or wind energy produced locally.In an effort to explore new business models that help position Element One into new travel segments, HES has aligned its zero-carbon aviation roadmap with Wingly, a French startup that offers flight sharing services for decentralized and regional air travel: “We analyzed the millions of destination searches made by the community of 200,000 pilots and passengers on our platform and confirm there is a tremendous need for inter-regional transport between secondary cities”, says Emeric de Waziers, CEO of Wingly. “By combining autonomous emission-free aircraft such as Element One, digital community-based platforms like Wingly and the existing high-density network of airfields, we can change the paradigm. France alone offers a network of more than 450 airfields but only 10% of these are connected by regular airlines. We will simply connect the remaining 90%.”Targeting a first flying prototype before 2025, HES is in the process of building a technical and commercial consortium involving both the aviation and hydrogen eco-systems.About HES Energy Systems (Singapore)HES Energy Systems specializes in building high performance hydrogen fuel cell systems to extend the flying range of autonomous aerial vehicles.  With a presence in Singapore since 2009, HES has grown to become a global leader in developing ultra-light fuel cells and hydrogen energy storage systems. Hired by tier-one UAV manufacturers and leading aerospace institutes around the world for over 12 years, HES has developed a variety of hydrogen storage approaches to continuously push the limits of on-board, off-grid or portable energy. HES’ parent company H3 Dynamics Holdings is backed by Japan’s SPARX representing Toyota Mirai Creation Fund, ACA Partners, and Capital Management Group.Source: HES via Green Car Congress read more

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Can A Tesla Model S Drive From Copenhagen To Oslo In 6

Recently, Nyland put the Model S P100D to a simple range test. Following this, he decided to travel at 125 mph for over an hour to test out the vehicle’s stamina. While the range test didn’t impress him as much as one would have expected, we were happy to report that the stamina test proved that the car can go and go without overheating, which is not what was the case in the past.Now, Bjørn wants to see if he can make it from Copenhagen to Oslo in six hours. According to Google maps, this should be the case, but remember, he’ll have to charge at some point. Road tripping in an EV is still a point of contention for many naysayers. Watch the video to see if he pulls it off.Video Description via Bjørn Nyland on YouTube:Copenhagen – Oslo challenge in Tesla Model S P100DLAccording to Google Maps, traveling from Copenhagen to Oslo takes about six hours. I wanted to match that time in a Tesla Model S.TESLA MODEL S Watch Tesla Model S Shooting Brake In Action Source: Electric Vehicle News Author Liberty Access TechnologiesPosted on October 16, 2018Categories Electric Vehicle News 19 photos Bjørn continues to test the potential of a Tesla Model S P100D.Our Norwegian speed skating friend got ahold of a Tesla Model S P100D recently and has performed several tests. This may be because the Model 3 has taken Tesla’s flagship car out of the limelight, or because Bjørn is a Model X owner, so many of his tests have been tackled in his personal Tesla: Optimus Prime. Regardless of the reason, it’s nice to have some fresh Model S video content to share, aside from the daily dose of drag races.Related Tesla Model S Stories: Watch Tesla Model S Drive 125 MPH For Over An Hour Bjørn Conducts Range Test On Tesla Model S P100D read more

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VW To Spend 50 Billion In Push To Launch 50 Electric Cars

first_imgHonestly, VW Group as a whole — arguably above any other automaker — has the finances, resources, and capacity to pull this off with ease. Based on its multitude of announcements, the company is well aware that it can (if it chooses) make this an incredible reality. Let’s cross our fingers and push hard for it to come to fruition.Following in the footsteps of Hyundai’s announcement that it has secured more battery cells to make to enough Kona EVs to satisfy growing U.S. demand, and also on the heels of Rivian’s huge announcement of a viable all-electric adventure-based pickup truck and 3-row SUV. Now, VW Group has announced another massive investment over the next five years, in an obvious attempt to keep up with the newfound switch to EVs. The company is also now increasingly touting its upcoming connected services and self-driving tech.As this press release reveals, VW has added a budget of another $50 billion between now and 2023, which will help efforts to release some 50 new electric vehicles by 2025. The automaker claims to have the capacity to manufacture up to 15 million EVs on its new MEB platform within that suggested time frame.Source: Automotive News Europe VW Turns To SK Innovation As Cell Supplier For U.S. Electric Cars VW Claims By 2020, Its Electric Cars Will Match Tesla At Half Price VW CEO Says Automaker Will Make Electric Cars Mainstream Ahh the EV announcements come daily from VW and while we’re truly excited about what’s to come, we can only hope that it’s all a reality in the making.How about a grand slew of affordable EVs that can perform like that of Tesla vehicles? How about long-range electric vehicles that you can buy just about anywhere and everywhere that are truly impressive in so many ways? We’re talking about a whole lineup of electric cars and SUVs that are designed to appeal to the masses. Volkswagen says it’s ready to make that happen.More Volkswagen EV News: Source: Electric Vehicle News Author Liberty Access TechnologiesPosted on November 16, 2018Categories Electric Vehicle Newslast_img read more

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Senate Remains Interested In FCPA Issues

first_imgGranted it has been approximately four years since the Senate held its Foreign Corrupt Practices hearing in November 2010.  (The House followed-up with an FCPA hearing in June 2011).FCPA reform legislation was never introduced (for potential reasons why – see this article), yet the Senate very much remains interested in FCPA issues.The Senate Judiciary Committee recently released this document which contains Attorney General Nominee Loretta Lynch’s responses to various Senator questions.The remainder of this post excerpts all FCPA related questions and Lynch’s answers.As highlighted below, the Q&A’s cover the following topics:  DOJ guidance, DOJ declinations, “FCPA abuses” (as stated in a series of questions), Andrew Weissman’s FCPA reform positions prior to recently re-joining the DOJ (see here for the prior post), international cooperation, FCPA reform (including a compliance defense), and the time it takes to resolve FCPA investigations.*****FROM SENATOR GRASSLEY (R-IA)Q: In 2012, the Department of Justice and Securities Exchange Commission (SEC) issued joint guidance detailing Foreign Corrupt Practices Act (FCPA) enforcement information and the agencies’ enforcement priorities. While the guidance clarified portions of the law and some of the agencies’ enforcement theories, many companies and individuals seeking to comply with the FCPA have asked for further, and continued, clarification. This request was expressed to Attorney General Eric Holder and Assistant Attorney General Leslie Caldwell during previous Committee hearings. a. If confirmed, will you commit to working with companies and individuals to further improve the Guidance?RESPONSE: If I am confirmed as Attorney General, I look forward to continuing the outreach efforts that the Department has been making with the private sector to understand their needs and concerns and, if necessary, update and/or improve the Guide.b. Will you commit to updating the Guidance, when necessary, to reflect changes in DOJ enforcement practices? RESPONSE: If I am confirmed as Attorney General, I look forward to continuing efforts that the Department has been making to provide meaningful guidance in the FCPA context where necessary and appropriate.In the area of FCPA enforcement, there is little guiding case law available for compliance practitioners to rely on. However, the FCPA Guidance that was issued in 2012 took an important first step in helping practitioners understand how the enforcement agencies’ interpret the statute. The Guidance includes six anonymized examples of declinations— instances where the DOJ and SEC declined to bring FCPA-related enforcement actions in recognition of the companies’ timely voluntary disclosures, meaningful cooperation, and sophisticated compliance policies and controls. The continued publication of FCPA declinations would foster greater FCPA compliance by providing practitioners with a better understanding of how the FCPA is interpreted. If confirmed, would you support increasing DOJ transparency regarding declination decisions? RESPONSE: As you know, the United States Attorney’s Manual provides a mechanism to allow for notification to an individual (or entity), where appropriate, that an investigation as to that individual (or entity) is being closed. If I am confirmed as Attorney General, I look forward to continuing the Department’s practice of providing meaningful guidance in the FCPA context (such as procedures to respond to opinion requests) and of actively pursuing and implementing means by which declinations and other information about the decision to prosecute, or not, can be responsibly and appropriately shared.FROM SENATOR CRUZ (R-TX)DOJ Foreign Corrupt Practices Act AbusesIn much the same way as civil forfeiture, critics of the FCPA note that the Department of Justice collects and retains for use (without further congressional approval or disbursal from the Treasury) fines paid in settlement of federal FCPA investigations. This ability to retain FCPA fines incentivizes not only a vigorous application of the FCPA, but also “creative” legal theories (which can lead to investigations of companies for potentially innocuous behavior). Critics of the FCPA, and the Department’s pursuit of FCPA investigations, point out that the combination of investigation and potential litigation expenses frequently drive what may be innocent companies to settle, which both cements the revenue source for the Department and prevents federal judges from having opportunities to interpret provisions of the FCPA.Do you agree or disagree with the claim that the ability of the Department of Justice to keep and use FCPA settlement fines incentivizes application of the FCPA? If you disagree with this claim, please provide a detailed explanation as to why. RESPONSE: I disagree with this claim, which I believe is built on a faulty premise regarding the process by which criminal fines and other financial penalties are paid and subsequently put to use. Fines for FCPA violations are not “kept” or “used” by the Department, and no such use incentivizes application of the FCPA. Rather, as with all cases, the Department considers the strength of the evidence and other long-standing policy considerations (see, e.g., United States Attorney’s Manual (USAM) 9-28.300) in determining whether to bring an FCPA prosecution.A company convicted of an FCPA violation pays any accompanying fine not to the Department but to the relevant U.S. district court clerk’s office. Those funds are then directed to the Crime Victim Fund, which is a U.S. Treasury fund created pursuant to Title 42, United States Code, Section 10601. Funds paid into the U.S. Treasury are not available for use by the Department except through the appropriations process or by statute.A company that settles an FCPA investigation through a non-prosecution or deferred prosecution agreement pays any accompanying financial penalty not to the Department but to the U.S. Treasury. Pursuant to Congressional authorization and strict Departmental oversight, a small percentage of these funds may be made available to the Department. More specifically, in 1993 Congress authorized the creation of a 3% working capital fund (“3% Fund”) for the Department. See Public Law 113-234, 28 C.F.R. Section 527. Three percent of penalties associated with certain financial recoveries, including through non-prosecution and deferred prosecution agreements, are paid into the 3% working capital fund. After rigorous review by the Collection Resources Allocation Board, overseen by the Justice Management Division, the Department may award funds from the 3% Fund to support certain litigation, data administration, and personnel costs.Has your office actually tried any FCPA cases to a verdict in federal court? If the answer is yes, please provide details about these cases. RESPONSE: The Eastern District of New York has participated in a number of significant FCPA investigations with the Fraud Section of the Criminal Division of the Department, and it continues to do so. To date, these investigations have resulted in two corporate resolutions: (1) In re Ralph Lauren, NPA, $882,000 penalty, press release at: http://www.justice.gov/opa/pr/ralph-lauren-corporation-resolves-foreign-corrupt-practices-actinvestigation-and-agrees-pay; and (2) In re Comverse Technology, Inc., NPA, $1.2 million penalty, press release: http://www.justice.gov/opa/pr/comverse-technology-inc-agrees-pay-12- million-penalty-resolve-violations-foreign-corrupt); and one guilty plea by Garth Peterson of Morgan Stanley (and a declination against Morgan Stanley) (press release: http://www.justice.gov/opa/pr/former-morgan-stanley-managing-director-pleads-guilty-roleevading-internal-controls-required). While the Department has conducted FCPA trials in many districts, the United States Attorney’s Office for the Eastern District of New York has not had an FCPA trial to date.As you know, the Criminal Division’s Fraud Section is charged with investigating and enforcing the criminal provisions of the FCPA. Recently, Andrew Weissmann was selected to be the Chief of the Fraud Section. Mr. Weissmann is a former prosecutor and FBI general counsel. In private practice, however, Mr. Weissmann has been an outspoken critic of DOJ’s FCPA program. Specifically, in a report36 Mr. Weissmann drafted for the U.S. Chamber of Commerce’s Institute for Legal Reform, he has recommended that: (1) a compliance defense to the FCPA should be added; (2) a company’s liability should be limited for the prior actions of a company it has acquired; (3) a “willfulness” element should be added for corporate criminal liability; (4) a company’s liability should be limited for the actions of a subsidiary; and (5) the definition of “foreign official” under the FCPA should be changed.Do you agree with any, some, or all of Weissmann’s proposals for reforming the FCPA? RESPONSE: It is my understanding that Mr. Weissmann made these comments while in private practice and in connection with his representation of the U.S. Chamber Institute for Legal Reform (“Chamber”). It is also my understanding that, in the intervening time period, the Department has met with the Chamber, as well as other stakeholders, to engage in a healthy and productive dialogue regarding the Department’s interpretation and application of the FCPA. If confirmed as Attorney General, I would continue to foster dialogue with the Chamber and other stakeholders regarding our FCPA program.Which of these changes (if any) do you think could be done administratively, as opposed to legislatively? RESPONSE: I do not support the proposed changes. Several of them would be a significant departure from general principles of corporate criminal law, effectively creating unique exceptions for FCPA cases that are unwarranted, are contrary to Congress’s intent in enacting the FCPA, and would impose often insurmountable obstacles to effective enforcement of the FCPA.In 2004, then-Deputy Attorney General (and current director of the Federal Bureau of Investigation) James Comey stated that “[the Department of Justice wants] real time enforcement, so that the public and potential white collar criminals see that misdeeds are swiftly punished.” Despite this statement, the 2014 OECD Foreign Bribery Report noted that “the average time taken (in years) to conclude foreign bribery cases has steadily increased over time, [from an average of 1.3 years in 2004] peaking at an average of 7.3 years taken to conclude the 42 cases in 2013.” Lengthy federal investigations not only place a tremendous financial burden on the targeted corporations and their shareholders, but also on taxpayers who shoulder the agency’s expenses for conducting the investigation.Do you agree or disagree with Director Comey’s statement regarding the value of real-time law enforcement? If you disagree with this statement, please provide a detailed explanation as to why. RESPONSE: I agree that law enforcement must move swiftly and responsibly in investigating both white collar and other criminal activity. I also agree that, for deterrence purposes, it is important to move quickly and bring charges against those individuals and companies that have engaged in criminal behavior. While the Department has been working diligently to find meaningful and reasonable ways to reduce the time white collar FCPA investigations take, the question’s reliance on the OECD Foreign Bribery Report is misplaced. As I understand it, the referenced statistic is based on an aggregate of all the OECD Working Group members’ cases, rather than isolating the time taken by the United States in its cases. Also, this statistic does not measure the length of the criminal investigation. Rather, it measures the time between the last criminal act and the sanction, increasing substantially the time measured, since the Department (or foreign law enforcement) might not learn about a potential violation until years after the last criminal act has occurred.Given that the FCPA Unit within the Department’s Fraud Section has expanded its personnel from 2004 to today, and given that the Department receives even more international cooperation today than it did in 2004, do you agree or disagree that the Department should be witnessing reduced investigative timelines for FCPA investigations rather than increased timelines? If you disagree with this statement, please provide a detailed explanation as to why. RESPONSE: Additional resources and cooperation are greatly appreciated and can often be key factors in expediting criminal investigations. However, they are only two of many factors that can influence the time it takes to conduct a successful investigation of any kind. Compared to other white collar investigations, the challenges associated with FCPA investigations can be much greater. Because of the nature of the offense, most of the evidence in these cases is typically located overseas. While international cooperation efforts have expanded significantly over the past ten years, the process for obtaining evidence from overseas is still time-consuming.Before you are confirmed to serve as the next Attorney General, will you or will you not commit to dramatically reducing the timeline of FCPA-related Fraud Unit investigations, in order to reduce the financial burden on potentially innocent corporations and reduce investigation-related taxpayer expenses? If you will not commit to reducing these investigative timelines, please provide a detailed explanation as to why. RESPONSE: Under my leadership, the Eastern District of New York has been committed to increasing the speed of its white collar investigations, including its FCPA investigations. As a result of the particular challenges of corporate and overseas investigations, however, the investigations can take a significant amount of time. While improvements in this area can be made, irresponsibly or artificially expediting an investigation solely for the sake of speed can harm the investigation and the pursuit of justice, as well as create greater harms to the targets, subjects, and witnesses in our investigations. If I am confirmed as Attorney General, you can be assured that the Department will continue to review each case on its merits and will move as expeditiously and responsibly as possible.Often, many of the countries with corrupt officials are the same countries that harbor terrorists, that seek to undermine U.S. foreign policy, and that have rampant bid rigging and illegal cartel conduct. On the opposite side of the equation, there are an increasing number of countries that have passed new anti-bribery statutes in the hope of curbing their own internal corruption problems and spurring legitimate economic growth.How will you marshal the criminal justice resources of the Department of Justice to enforce the FCPA in a way that helps in the fight against terrorism, cartel conduct, and international money laundering? Please provide a detailed explanation, based on your current experience as United States Attorney for the Eastern District of New York, of how you intend to tackle the problem. RESPONSE: As the United States Attorney for the Eastern District of New York, I am well aware of the link between corruption, corrupt regimes, and transnational crime, including economic crime, human trafficking, narcotics trafficking, money laundering, and even terrorism. In addition to prosecuting foreign corruption, narcotics trafficking, money laundering, and terrorism cases, the Department works closely with its counterparts throughout the U.S. government to devise and implement robust anticorruption strategies. For example, my Office has worked closely with the intelligence community on terrorism and corruption-related matters. The Department further participates, along with colleagues in other agencies in the U.S. government, in developing anticorruption policies through various international organizations and anticorruption conventions, including the Organization for Economic Cooperation and Development’s Working Group on Bribery, the G-7, the G-20, and the U.N. Convention Against Corruption. The Department also consults with civil society organizations involved in the battle against corruption. If confirmed as the Attorney General, I would continue to ensure that fighting corruption overseas, as well as domestically, remains a top priority for the Department. I would ensure that resources are appropriately directed to enforcing U.S. laws targeting foreign corruption, recovery of assets stolen by kleptocrats, and corrupt regimes.Given that more and more countries are enacting and enforcing anti-bribery statutes, would you agree or disagree that the FCPA ought to be amended to restrict FCPA jurisdiction to countries that do not have a prima facie anticorruption infrastructure? If you disagree with this statement, please provide a detailed explanation as to why. RESPONSE: Such an exception would be unique under federal law. I disagree with this approach, as I believe it would do harm to the Department’s anticorruption efforts. The Department works closely with countries that are developing their own anticorruption infrastructures, and we are well aware that it can take years of persistent effort to create an effective and holistic response to corruption of domestic and foreign officials.As a recent OECD Report on Foreign Bribery noted, enforcement of existing anticorruption statutes, particularly those targeting foreign bribery, is improving but has a long way to go to see consistent and effective enforcement even among top economies in the world.The Department of Justice generally emphasizes the benefit of voluntary self-disclosure to, and voluntary cooperation with, FCPA investigations. Corporations are increasingly questioning the benefit, however, of rushing toward self-disclosure without demonstration of some sort of legal or cost benefit for doing so. To address this, some practitioners have suggested that the FCPA should contain a “safe harbor” from criminal prosecution for corporations that (1) have robust compliance programs, (2) self-disclose potential FCPA violations, and (3) cooperate fully with the Department’s investigation, akin to what the Antitrust Division has for cartel enforcement. (The Department would, of course, be able to continue to obtain non-criminal penalties for violations.) Do you agree or disagree with the statement that there should be an FCPA “safe harbor provision” to help corporations that are trying to do the right thing? If you disagree with this statement, please provide a detailed explanation as to why. RESPONSE: I do not believe a “safe harbor provision” is necessary or desirable. Both the U.S. Sentencing Guidelines and the Department of Justice already provide significant benefits for companies that have robust compliance programs, self-disclose potential FCPA violations, and cooperate fully with the Department’s investigation. Indeed, in a recent FCPA matter, the Criminal Division and the Eastern District of New York declined to prosecute Morgan Stanley based on many of those factors, among others, despite the fact that one of its Managing Directors bribed a foreign official to obtain business for and on behalf of Morgan Stanley.If you agree with the concept of an FCPA safe harbor provision, please describe what the structure or contours of such a safe harbor provision should be, and how you would implement that provision. Please provide a detailed explanation, based on your current experience as United States Attorney for the Eastern District of New York, of how you would write and implement such a provision. RESPONSE: The factors outlined in your question are important considerations in all FCPA cases, but I do not believe that a “safe harbor provision” is necessary or desirable.Members of the business community, practitioners, commentators, and even members of Congress have expressed frustration with the Department of Justice’s failure to publicize declined FCPA prosecutions, even where there is public knowledge that a particular corporation is under investigation. This practice may have several negative effects, including preventing corporations from having clarity about what type of conduct is considered acceptable. Given the Department’s financial incentive to ensure robust application of the FCPA, there is concern that this refusal to publish decline-to-prosecute information is intended to protect the FCPA fine-based revenue source for the Department.Would you agree or disagree with the statement that FCPA decline-to-prosecute decisions should be made available to the public? If you disagree with this statement, please provide a detailed explanation as to why.RESPONSE: I agree that the Department should continue to explore ways by which it can responsibly share information while protecting the many sensitive interests that federal, criminal investigations implicate. The Department has a longstanding general practice of refraining from discussing non-public information on matters it has declined to prosecute. This practice is designed to protect ongoing investigations, privacy rights and other interests of uncharged parties, and sensitive, internal law enforcement deliberations. This practice and these considerations apply across the enforcement of all federal criminal laws.Nevertheless, I must emphasize that the Department does pursue means by which declinations and other information about the decision to prosecute can be responsibly shared with entities or individuals under investigation, the business community, practitioners, commentators, and members of Congress. The United States Attorney’s Manual (USAM) describes situations in which a United States Attorney can exercise discretion to provide notice that an investigation is being closed. See USAM § 9-11.155. Further, in the last two years, the Department has made great efforts to provide more information and transparency in the area of the FCPA, including the publication of A Resource Guide to the U.S. Foreign Corrupt Practices Act (the “Resource Guide”). The Resource Guide, which was written by the Department and the U.S. Securities and Exchange Commission (SEC), provides the public with extensive information about the Department’s FCPA enforcement approach and priorities. It contains a section on declinations and sets out criteria prosecutors consider in declining to bring a prosecution under the FCPA. In addition, the Department responds to opinion requests concerning its enforcement intent about actions that may be perceived as violating the anti-bribery provisions of the FCPA. See Title 15, United States Code, Sections 78dd-l(e) and 78dd-2(f). These opinion letters provide significant additional insight into the Department’s enforcement views, as well as transparency for companies, individuals, and practitioners as to what is acceptable or not.Before you are confirmed to serve as the next Attorney General, will you or will you not commit to publishing information about the FCPA cases that the Department has decided not to pursue or prosecute? If you will not commit to publishing this information, please provide a detailed explanation as to why. RESPONSE: I will commit to continuing the Department’s practice of actively pursuing and implementing means by which declinations and other information about the decision to prosecute, or not, can be responsibly and appropriately shared. As detailed in my answer to the preceding question, the United States Attorney’s Manual already provides a mechanism to provide notice that an investigation is being closed. I also commit to continuing the Department’s recent efforts to provide more information and transparency, as it did by publishing the Resource Guide.last_img read more

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Classifying heart failure patients based on redox status may help personalize treatment

first_imgJun 6 2018For more than six decades, oxidative stress has been linked to heart failure, a progressive weakening of the heart muscle that can lead to death. While antioxidant supplements such as vitamin C, vitamin B and beta-carotene have been widely used in heart failure, they often prove ineffective.Rajasekaran Namakkal-Soorappan, Ph.D., assistant professor of Molecular and Cellular Pathology, School of Medicine at the University of Alabama at Birmingham and colleagues at the PSG-Institute of Medical Sciences & Research, Coimbatore, India, sought to determine whether some heart failure patients might have reductive stress instead of oxidative stress, and whether that condition and its related mechanisms might help personalize treatment of heart failure patients, resulting in better outcomes.Namakkal-Soorappan and colleagues Thiagarajan Sairam, Ph.D., and Ramalingam Sankaran, M.D., recruited patients at PSG Hospitals and found that classifying heart failure patients based on the oxidant vs. antioxidant levels in the blood, known as the circulating redox status, may serve as a predictive tool for guiding personalized antioxidant therapies.Specifically, they found that members of a subgroup of heart failure patients have a hyper-reductive state, called reductive stress, and some have normal redox states. This raises some interesting questions about one of the most prevalent health issues facing Americans today.”We are hypothesizing that the general treatment of antioxidants for heart failure may not be beneficial for a subset of heart failure patients,” Namakkal-Soorappan said. “Patients with normal redox may not need any antioxidants. There is very solid evidence that antioxidants seem to fail in some patients, possibly because the right antioxidant was not used. The specificity of antioxidants is very important for its use.”The study, “Evidence for a hyper-reductive redox in a sub-set of heart failure patients,” was published in the Journal of Translational Medicine on May 18. While sample size was relatively small -; 54 heart failure patients and 42 healthy controls -; the results could impact how heart failure patients are treated and could guide personalized antioxidant therapies.”This was the first evidence to correlate some heart patients’ having too many antioxidants,” Namakkal-Soorappan said.The study used the circulatory redox state to separate the heart failure patients into normal redox, hyper-oxidative and hyper-reductive groups. A majority of patients, 42 percent, exhibited a hyper-oxidative state; nearly an equal number, 41 percent, exhibited a normal redox state; and 17 percent exhibited a hyper-reductive state.Related StoriesStroke should be treated 15 minutes earlier to save lives, study suggestsResearch opens possibility of developing single-dose gene therapy for inherited arrhythmiasImplanted device uses microcurrent to exercise heart muscle in cardiomyopathy patients”This finding suggests a strong implication for reductive stress in the progression of heart failure, but the mechanisms are unknown,” Namakkal-Soorappan said.Namakkal-Soorappan, along with Ivor Benjamin, M.D., and their research team at the University of Utah Department of Medicine, first discovered in 2007 that hypertrophy, or enlargement of the heart, is caused by a chaperone protein, alpha-B-crystallin, that is mutated in cardiac myocytes, the muscle cells of the heart associated with reductive stress.”The cardiac cells respond to stress by enlarging,” Namakkal-Soorappan said. “Patients who have this genetic mutation develop hypertrophy.”This enlargement normally occurs when patients are in their 40s or older, as aging usually leads to oxidative stress.”However, when we closely studied this mutated gene in animal models over their lifespans, transgenic mice developed hypertrophy in six to eight months, which is equivalent to a human being in his or her late 30s, and to our surprise, these mice had excess levels of antioxidants to create reductive stress,” he said. “We thought it could be oxidative because of aging, but it’s not.” We decided to use the terminology of reductive stress -; originally named in the 1960s and lately as seen in patients with Alzheimer’s disease, but not often described in pathophysiology of other major human diseases.”What does this mean clinically?Though the sample size is not sufficient to make definitive conclusions, it simply means that patients come in diverse forms, though their clinical diagnosis may be the same, and therefore in terms of treatment “one size does not fit all.” Prescribing antioxidant treatment to all may not only not be beneficial, but could result in harm. The good news is that testing for reductive stress is accomplished easily in about two hours with a blood test, says co-senior author Ramalingam Sankaran, dean and professor at the PSG Institute of Medical Sciences & Research, Coimbatore, Tamil Nadu, India. This medical research was generously supported in part by PSG & Sons’ Charities in Coimbatore.Future steps include a study to screen for reductive stress in several different heart diseases that lead to heart failure, with a long-term goal of conducting collaborative research as part of a multi-site clinical trial, Namakkal-Soorappan says.”We would like to study a couple thousand patients and screen them for genetic mutations, and analyze for correlations to study how human beings develop this reductive stress,” Drs. Thiagarajan and Namakkal-Soorappan said.Source: https://www.uab.edu/news/research/item/9514-identifying-a-subgroup-of-heart-failure-patients-could-lead-to-improved-carelast_img read more

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Study shows shortterm improvements in blood vessel function after consuming red raspberries

first_imgJul 11 2018A recent randomized controlled trial, published in the  Archives of Biochemistry and Biophysics, provides insights on the promising outcomes of short-term improvements in blood vessel function among healthy males who consumed dietary achievable amounts of red raspberries.The subjects – ten healthy males aged 18 to 35 – consumed drinks prepared with 200g and 400g of frozen raspberries containing 201 or 403 mg of total polyphenols, or a matched control drink in terms of macro and micronutrient content, color, and taste.Researchers investigated the vascular effects of the subjects at baseline, 2 hours-post consumption and 24 hours-post consumption of the raspberry and control test drinks. Participants consuming the red raspberry drink showed improved flow-mediated dilation (FMD), an established biomarker of cardiovascular disease risk. FMD increased significantly at 2 hours post-consumption of the raspberry drink when compared with the change in FMD due to the control drink, and this maintained at 24 hours after consumption.Related Stories’Eye-in-a-dish’ model helps scientists to uncover ‘surprising’ AMD gene variantScientists create a functioning 3D printed heartOne-fifth of U.S. surgeons still ‘overusing’ riskier method to create kidney dialysis access, study findsAt 2 hours post-consumption of both raspberry drinks, ellagic acid, found in plasma and urine correlated with FMD. At 24 hours post-consumption of the 200g raspberry drink, urolithin-A-3-glucuronide and urolithin-A-sulfate correlated with FMD. No significant differences were found between FMD improvements after consumption of the 200g and 400g raspberry drinks.”The research study suggests that ellagitannins, a type of natural compounds present in red raspberries, may play a role in driving the positive effects seen on blood vessel function in the study’s participants,” commented Dr. Ana Rodriguez-Mateos, principal investigator and senior author of the study from the Department of Nutritional Sciences, Faculty of Life Sciences and Medicine of King’s College London.”We’re excited about these findings and what they may potentially add to the growing list of benefits from consuming red raspberries,” commented Tom Krugman, Executive Director of the National Processed Raspberry Council (NPRC).Further studies will need to show whether these results translate into long-term health benefits in the general population by looking at larger study groups over longer timeframes.Source: http://www.redrazz.org/blog/participants-in-new-human-study-experience-short-term-improved-vascular-function-after-consuming-red-raspberries/last_img read more

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What would happen if all Americans went vegan

first_img Country * Afghanistan Aland Islands Albania Algeria Andorra Angola Anguilla Antarctica Antigua and Barbuda Argentina Armenia Aruba Australia Austria Azerbaijan Bahamas Bahrain Bangladesh Barbados Belarus Belgium Belize Benin Bermuda Bhutan Bolivia, Plurinational State of Bonaire, Sint Eustatius and Saba Bosnia and Herzegovina Botswana Bouvet Island Brazil British Indian Ocean Territory Brunei Darussalam Bulgaria Burkina Faso Burundi Cambodia Cameroon Canada Cape Verde Cayman Islands Central African Republic Chad Chile China Christmas Island Cocos (Keeling) Islands Colombia Comoros Congo Congo, the Democratic Republic of the Cook Islands Costa Rica Cote d’Ivoire Croatia Cuba Curaçao Cyprus Czech Republic Denmark Djibouti Dominica Dominican Republic Ecuador Egypt El Salvador Equatorial Guinea Eritrea Estonia Ethiopia Falkland Islands (Malvinas) Faroe Islands Fiji Finland France French Guiana French Polynesia French Southern Territories Gabon Gambia Georgia Germany Ghana Gibraltar Greece Greenland Grenada Guadeloupe Guatemala Guernsey Guinea Guinea-Bissau Guyana Haiti Heard Island and McDonald Islands Holy See (Vatican City State) Honduras Hungary Iceland India Indonesia Iran, Islamic Republic of Iraq Ireland Isle of Man Israel Italy Jamaica Japan Jersey Jordan Kazakhstan Kenya Kiribati Korea, Democratic People’s Republic of Korea, Republic of Kuwait Kyrgyzstan Lao People’s Democratic Republic Latvia Lebanon Lesotho Liberia Libyan Arab Jamahiriya Liechtenstein Lithuania Luxembourg Macao Macedonia, the former Yugoslav Republic of Madagascar Malawi Malaysia Maldives Mali Malta Martinique Mauritania Mauritius Mayotte Mexico Moldova, Republic of Monaco Mongolia Montenegro Montserrat Morocco Mozambique Myanmar Namibia Nauru Nepal Netherlands New Caledonia New Zealand Nicaragua Niger Nigeria Niue Norfolk Island Norway Oman Pakistan Palestine Panama Papua New Guinea Paraguay Peru Philippines Pitcairn Poland Portugal Qatar Reunion Romania Russian Federation Rwanda Saint Barthélemy Saint Helena, Ascension and Tristan da Cunha Saint Kitts and Nevis Saint Lucia Saint Martin (French part) Saint Pierre and Miquelon Saint Vincent and the Grenadines Samoa San Marino Sao Tome and Principe Saudi Arabia Senegal Serbia Seychelles Sierra Leone Singapore Sint Maarten (Dutch part) Slovakia Slovenia Solomon Islands Somalia South Africa South Georgia and the South Sandwich Islands South Sudan Spain Sri Lanka Sudan Suriname Svalbard and Jan Mayen Swaziland Sweden Switzerland Syrian Arab Republic Taiwan Tajikistan Tanzania, United Republic of Thailand Timor-Leste Togo Tokelau Tonga Trinidad and Tobago Tunisia Turkey Turkmenistan Turks and Caicos Islands Tuvalu Uganda Ukraine United Arab Emirates United Kingdom United States Uruguay Uzbekistan Vanuatu Venezuela, Bolivarian Republic of Vietnam Virgin Islands, British Wallis and Futuna Western Sahara Yemen Zambia Zimbabwe Looking at the nutritional content of crops now produced, the team also found that a plant-only system wouldn’t be able to meet the U.S. population’s requirements for calcium, vitamins A and B12, and a few key fatty acids. “With carefully balanced rations, you can meet all of your nutrient requirements with a vegetarian diet,” White says. “But the types of foods that seem to do that, we don’t currently produce in sufficient quantities to make it a sustainable diet for the entire population.”Some researchers take issue with the study’s assumptions—for example that fruit and vegetable production wouldn’t make up a bigger part of the pie in a plant-only agricultural system. “[We] could yield a better nutrient profile if we do restructure the land use,” noted Joan Sabate, a nutritionist at Loma Linda University in California.Mario Herrero, an agricultural researcher at the Commonwealth Scientific and Industrial Research Organisation in St. Lucia, Australia, also thinks the team’s estimate of reductions in greenhouse gas emissions may be low. That’s because the study didn’t take into account how animal-free diets would affect imports, which make up a large part of the U.S. meat market. If Americans stop importing meat, it could lead to a reduction in greenhouse gas emissions in the countries that produce it, like Brazil, he says. “The full repercussions of doing something like this are rarely complete,” Herrero adds. “But [this study] is a valiant attempt.” Click to view the privacy policy. Required fields are indicated by an asterisk (*) Livestock, including cattle, are a significant source of greenhouse gas emissions. Chad Ehlers/Stock Connection/Aurora Photos Sign up for our daily newsletter Get more great content like this delivered right to you! Countrycenter_img Consider the hamburger. Producing this staple of the U.S. diet takes 25 kilograms of animal feed, 25 square meters of land, and about 220 liters of water—all for four patties. Statistics like those have persuaded some scientists and environmental activists that eating less meat could have a big impact on carbon and other greenhouse gas emissions. But what would happen if every American made the switch to a plant-only diet? According to a new study, a nation of 320 million vegans would reduce greenhouse gas emissions from agriculture by some 28%, far less than the amount now produced by the livestock industry. The authors claim the switch could also lead to deficiencies in key nutrients—including calcium and several vitamins.“Our logic was to start at the extreme scenario [and work backward from that],” says Robin White, the study’s lead author and an animal sciences researcher at Virginia Polytechnic Institute and State University in Blacksburg. She and fellow animal sciences researcher Mary Beth Hall, of the U.S. Department of Agriculture’s Dairy Forage Research Center in Madison, began by estimating the impact of converting all land now used by the livestock industry to cropland for human food. That would increase the amount of agricultural waste—corn stalks, potato waste, and other inedibles now fed to livestock—and eliminate the animals that now eat much of it. Burning the excess waste would add some 2 million tons of carbon to the atmosphere, they estimate. Fertilizer demands would also go up while the supply of animal manure dwindled. That would mean making more artificial fertilizer, adding another 23 million tons of carbon emissions per year.As a result, although animals now make up some 49% of agricultural emissions in the United States, a vegan nation would eliminate far less than that. Annual emissions would drop from 623 million tons to 446 million tons a year, the team reports today in the Proceedings of the National Academy of Sciences. Email By Katie LanginNov. 13, 2017 , 3:15 PM What would happen if all Americans went vegan?last_img read more

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Italys Mount Etna could be collapsing into the sea

first_img Italy’s Mount Etna could be collapsing into the sea Felix Gross For decades, scientists have known that the southeastern slopes of Mount Etna, an active volcano on the eastern shore of Sicily in Italy, are shifting toward the sea about 2 or 3 centimeters each year. Now, they have a better idea of why this is happening, and it’s making them worried.In a new study, scientists gathered data from seafloor instruments that allowed them to track the movement of the volcano’s submarine slopes over time. For most of the 15-month period they studied, nothing happened. But during an 8-day period in May 2017, Mount Etna’s southeastern flank moved 4 centimeters to the east, the researchers report online today in Science Advances.That’s a much larger movement than has been recorded on land, suggesting the southeastern flank of the volcano is collapsing under its own weight. There’s no telling whether, or when, this slow-motion landslide will really let loose, but the researchers note that sudden slumps of undersea material have created locally devastating tsunamis in other parts of the world.center_img By Sid PerkinsOct. 10, 2018 , 2:00 PMlast_img read more

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Despite scathing harassment report UNAIDS board gives agency head a reprieve for

first_img Country * Afghanistan Aland Islands Albania Algeria Andorra Angola Anguilla Antarctica Antigua and Barbuda Argentina Armenia Aruba Australia Austria Azerbaijan Bahamas Bahrain Bangladesh Barbados Belarus Belgium Belize Benin Bermuda Bhutan Bolivia, Plurinational State of Bonaire, Sint Eustatius and Saba Bosnia and Herzegovina Botswana Bouvet Island Brazil British Indian Ocean Territory Brunei Darussalam Bulgaria Burkina Faso Burundi Cambodia Cameroon Canada Cape Verde Cayman Islands Central African Republic Chad Chile China Christmas Island Cocos (Keeling) Islands Colombia Comoros Congo Congo, the Democratic Republic of the Cook Islands Costa Rica Cote d’Ivoire Croatia Cuba Curaçao Cyprus Czech Republic Denmark Djibouti Dominica Dominican Republic Ecuador Egypt El Salvador Equatorial Guinea Eritrea Estonia Ethiopia Falkland Islands (Malvinas) Faroe Islands Fiji Finland France French Guiana French Polynesia French Southern Territories Gabon Gambia Georgia Germany Ghana Gibraltar Greece Greenland Grenada Guadeloupe Guatemala Guernsey Guinea Guinea-Bissau Guyana Haiti Heard Island and McDonald Islands Holy See (Vatican City State) Honduras Hungary Iceland India Indonesia Iran, Islamic Republic of Iraq Ireland Isle of Man Israel Italy Jamaica Japan Jersey Jordan Kazakhstan Kenya Kiribati Korea, Democratic People’s Republic of Korea, Republic of Kuwait Kyrgyzstan Lao People’s Democratic Republic Latvia Lebanon Lesotho Liberia Libyan Arab Jamahiriya Liechtenstein Lithuania Luxembourg Macao Macedonia, the former Yugoslav Republic of Madagascar Malawi Malaysia Maldives Mali Malta Martinique Mauritania Mauritius Mayotte Mexico Moldova, Republic of Monaco Mongolia Montenegro Montserrat Morocco Mozambique Myanmar Namibia Nauru Nepal Netherlands New Caledonia New Zealand Nicaragua Niger Nigeria Niue Norfolk Island Norway Oman Pakistan Palestine Panama Papua New Guinea Paraguay Peru Philippines Pitcairn Poland Portugal Qatar Reunion Romania Russian Federation Rwanda Saint Barthélemy Saint Helena, Ascension and Tristan da Cunha Saint Kitts and Nevis Saint Lucia Saint Martin (French part) Saint Pierre and Miquelon Saint Vincent and the Grenadines Samoa San Marino Sao Tome and Principe Saudi Arabia Senegal Serbia Seychelles Sierra Leone Singapore Sint Maarten (Dutch part) Slovakia Slovenia Solomon Islands Somalia South Africa South Georgia and the South Sandwich Islands South Sudan Spain Sri Lanka Sudan Suriname Svalbard and Jan Mayen Swaziland Sweden Switzerland Syrian Arab Republic Taiwan Tajikistan Tanzania, United Republic of Thailand Timor-Leste Togo Tokelau Tonga Trinidad and Tobago Tunisia Turkey Turkmenistan Turks and Caicos Islands Tuvalu Uganda Ukraine United Arab Emirates United Kingdom United States Uruguay Uzbekistan Vanuatu Venezuela, Bolivarian Republic of Vietnam Virgin Islands, British Wallis and Futuna Western Sahara Yemen Zambia Zimbabwe It’s too early to say, however, whether Sidibé’s job is safe until next summer. Sweden, UNAIDS’s second largest donor, announced earlier this week that it would freeze support for the agency until Sidibé leaves. Other donors—including the United States, the largest donor—have yet to take such a public stance. Click to view the privacy policy. Required fields are indicated by an asterisk (*) Sign up for our daily newsletter Get more great content like this delivered right to you! Country A board that oversees the Joint United Nations Programme on HIV/AIDS (UNAIDS) in Geneva, Switzerland, the global command center in the fight against the infectious disease, has resisted calls to immediately recommend the firing of the agency’s executive director in the wake of a report that found UNAIDS rife with harassment, bullying, and abuses of power. The Programme Coordinating Board, which finished a meeting today that included discussions of the report, instead established a working group to further consider the allegations and criticisms. (The board itself cannot fire the UNAIDS head, but it can recommend the action to the United Nations.)UNAIDS Executive Director Michel Sidibé, who initiated the review that ultimately called for his ouster, spoke at the board’s meeting and asked to stay on through June 2019 to oversee an “agenda for change” that his management team has drafted in response to the report. “We don’t have a moment to lose in moving forward our management response,” Sidibé said in a statement. “I look forward to an inclusive, transparent, and open dialogue and collaboration with staff in shaping a new UNAIDS.” In the long run, the future of UNAIDS itself may be in jeopardy, says Sten Vermund, who heads the Yale School of Public Health. The panel contends that UNAIDS’s problems stem from its unique position within the United Nations system, which has led to it being “governed in a way that has produced a vacuum of accountability.” Vermund suggests this could lead to soul searching about whether UNAIDS should continue to exist as a special agency. “Is UNAIDS serving the purpose for which it was formed, and could those functions be better subsumed in the [World Health Organization]?” he wonders. “Ultimately, you have to ask that question.” Michel Sidibé By Jon CohenDec. 13, 2018 , 4:05 PM DENIS BALIBOUSE/REUTERS Despite scathing harassment report, UNAIDS board gives agency head a reprieve for now Emaillast_img read more

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Martian methane—spotted in 2004—has mysteriously vanished

first_img Email TG medialab/ESA Martian methane—spotted in 2004—has mysteriously vanished Click to view the privacy policy. Required fields are indicated by an asterisk (*) The Trace Gas Orbiter arrived at Mars in 2016. Mars’s methane has gone missing. Scientists first detected traces of the gas—a critical indicator of life on Earth—in the planet’s atmosphere decades ago. But today, researchers reported that a European satellite hasn’t spotted a single trace of methane. The finding, if it holds up, could complicate scientific dreams that martian microbes might be spewing the gas in the planet’s subsurface.The Mars Express orbiter first detected hints of methane in the martian atmosphere in 2004. But some scientists said the orbiter’s instruments that found it—at a level of 10 parts per billion (ppb)—weren’t sensitive enough to produce reliable results. Ten years later, NASA’s Curiosity rover detected a methane spike of 7 ppb from its base in Gale crater, which lasted several months. Several years later, Curiosity’s scientists then discovered a minute seasonal cycle, with methane levels peaking at 0.7 ppb in the late northern summer.To settle this mystery, the European Space Agency’s Trace Gas Orbiter (TGO), which arrived at Mars in 2016, this year began to scan the atmosphere for methane. Two of the TGO’s spectrometers—a Belgian instrument called NOMAD and a Russian one called ACS—were designed to detect methane in such low concentrations that researchers were sure they would. Both instruments, which analyze horizontal slices of the martian atmosphere backlit by the sun, are working well, scientists on the team said today at a semiannual meeting of the American Geophysical Union in Washington, D.C. There’s still some noise to clean up, said Ann Carine Vandaele, NOMAD’s principal investigator and a planetary scientist at the Royal Belgian Institute for Space Aeronomy in Brussels, in her talk. “But we already know we can’t see any methane.”center_img Sign up for our daily newsletter Get more great content like this delivered right to you! Country Country * Afghanistan Aland Islands Albania Algeria Andorra Angola Anguilla Antarctica Antigua and Barbuda Argentina Armenia Aruba Australia Austria Azerbaijan Bahamas Bahrain Bangladesh Barbados Belarus Belgium Belize Benin Bermuda Bhutan Bolivia, Plurinational State of Bonaire, Sint Eustatius and Saba Bosnia and Herzegovina Botswana Bouvet Island Brazil British Indian Ocean Territory Brunei Darussalam Bulgaria Burkina Faso Burundi Cambodia Cameroon Canada Cape Verde Cayman Islands Central African Republic Chad Chile China Christmas Island Cocos (Keeling) Islands Colombia Comoros Congo Congo, the Democratic Republic of the Cook Islands Costa Rica Cote d’Ivoire Croatia Cuba Curaçao Cyprus Czech Republic Denmark Djibouti Dominica Dominican Republic Ecuador Egypt El Salvador Equatorial Guinea Eritrea Estonia Ethiopia Falkland Islands (Malvinas) Faroe Islands Fiji Finland France French Guiana French Polynesia French Southern Territories Gabon Gambia Georgia Germany Ghana Gibraltar Greece Greenland Grenada Guadeloupe Guatemala Guernsey Guinea Guinea-Bissau Guyana Haiti Heard Island and McDonald Islands Holy See (Vatican City State) Honduras Hungary Iceland India Indonesia Iran, Islamic Republic of Iraq Ireland Isle of Man Israel Italy Jamaica Japan Jersey Jordan Kazakhstan Kenya Kiribati Korea, Democratic People’s Republic of Korea, Republic of Kuwait Kyrgyzstan Lao People’s Democratic Republic Latvia Lebanon Lesotho Liberia Libyan Arab Jamahiriya Liechtenstein Lithuania Luxembourg Macao Macedonia, the former Yugoslav Republic of Madagascar Malawi Malaysia Maldives Mali Malta Martinique Mauritania Mauritius Mayotte Mexico Moldova, Republic of Monaco Mongolia Montenegro Montserrat Morocco Mozambique Myanmar Namibia Nauru Nepal Netherlands New Caledonia New Zealand Nicaragua Niger Nigeria Niue Norfolk Island Norway Oman Pakistan Palestine Panama Papua New Guinea Paraguay Peru Philippines Pitcairn Poland Portugal Qatar Reunion Romania Russian Federation Rwanda Saint Barthélemy Saint Helena, Ascension and Tristan da Cunha Saint Kitts and Nevis Saint Lucia Saint Martin (French part) Saint Pierre and Miquelon Saint Vincent and the Grenadines Samoa San Marino Sao Tome and Principe Saudi Arabia Senegal Serbia Seychelles Sierra Leone Singapore Sint Maarten (Dutch part) Slovakia Slovenia Solomon Islands Somalia South Africa South Georgia and the South Sandwich Islands South Sudan Spain Sri Lanka Sudan Suriname Svalbard and Jan Mayen Swaziland Sweden Switzerland Syrian Arab Republic Taiwan Tajikistan Tanzania, United Republic of Thailand Timor-Leste Togo Tokelau Tonga Trinidad and Tobago Tunisia Turkey Turkmenistan Turks and Caicos Islands Tuvalu Uganda Ukraine United Arab Emirates United Kingdom United States Uruguay Uzbekistan Vanuatu Venezuela, Bolivarian Republic of Vietnam Virgin Islands, British Wallis and Futuna Western Sahara Yemen Zambia Zimbabwe By Paul VoosenDec. 12, 2018 , 5:30 PM The team’s initial results show no detection of methane down to a minute level of 50 parts per trillion, with their observations going down nearly all the way to the martian surface.The results are a surprise, says Chris Webster, a planetary scientist at the Jet Propulsion Laboratory in Pasadena, California, who leads the methane-sensing instrument on Curiosity. He expected the TGO to pick up at least a 0.2-ppb signal. But he’s still optimistic: It took his team 6 months to detect the methane spike and years to find the seasonal background methane cycle. “I’m confident that over time there will be a consistency between the two data sets.”The Curiosity team suspects the methane cycle comes from microseeps in the planet’s subsurface, either from living or geological sources, not from outside the planet. The TGO could validate that, given that it seems to show no methane falling down through the atmosphere. “The methane is not coming from above,” Webster says. “That’s a big result.”It’s also confusing: For example, scientists suspect that hundreds of tons of organic carbon pour into the martian atmosphere each year from solar system dust, reacting with solar radiation to form methane, say John Moores, a planetary scientist at York University in Toronto, Canada. “Where is all that carbon going?”Gale crater is unlikely to be the only spot on Mars to see such seeps, says Sushil Atreya, a planetary scientist at the University of Michigan in Ann Arbor and a member of the Curiosity science team. But even if there are 5000 similar seeps, the signal that mixes into the atmosphere will be small. “I actually did the calculation,” he says. “It’s going to average out to be a very, very low value, nondetectable.”For now, the methane mystery has only deepened. The TGO will keep running until 2022, enough to capture at least a couple martian years. Its data will grow more precise and its detection limits will drop. And perhaps then scientists will know whether their hopes for methane-spewing microbes, already on life support, have reached an end.last_img read more

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Former Rep Slams Maleah Davis Mother

first_img Meghan McCain Whines That She Can’t Attack llhan Omar Because Trump Is Too Racist Maleah Davis is still missing and many people have suspected, the four-year-old’s mother Brittany Bowens knows much more than she is revealing. Her former representation, activist Quanell X, has cut ties with her and he slammed her in a recent interview.See Also: A Timeline Of Dallas Cop Amber Guyger Killing Botham Jean In His Own HomeIn an interview with KHOU, Quanell said, “There was not a lot of tears. She was always calm, fluid, clear.  Now whenever there was a public thing, she would always break down.” He continued, “Ain’t no way in hell a parent with common sense would have handled this entire situation the way Brittany handled this entire situation.” More By NewsOne Staff Emantic "EJ" Fitzgerald Braford Jr. Jesse Jackson Demands ‘Justice Now’ At EJ Bradford’s Moving Funeral Ceremony BREAKING: missing 4YO Maleah Davis was removed from her home in August by CPS. They tell us it was due to allegations of physical abuse, related to Maleah’s head injury, which required several brain surgeries. She was returned home in Feb. @abc13houston pic.twitter.com/jiAq1E6XVU— Shelley Childers (@shelleyabc13) May 6, 2019 Police Chief Art Acevedo told KHOU he “would not discuss the status of Bowens.” Sadly, he also said, “We already know and believe that she is dead and we need to bring her home.”Vence originally told Sgt. Mark Holbrook of the Houston Police Department’s Homicide Division that he, Maleah and his two-year-old son were on their way to George Bush Intercontinental Airport Friday night to pick up Maleah’s mother, who was flying in from Massachusetts. Vence said he heard a “popping noise” and pulled over. He said a blue pickup truck pulled up behind his vehicle and two Hispanic males got out and hit him in the head. He said he lost consciousness and woke up at 6 p.m. the next day. He said Maleah was missing but his son was still there. Vence claimed he then walked to a hospital, received treatment and then reported Maleah as missing.The Associated Press reported that Houston authorities said Vence’s account has “changed several times.”Maleah was reportedly last seen wearing a pink bow in her hair with a light blue zip-up jacket, blue jeans and gray, white and pink sneakers. She has black hair and brown eyes and stands 3 feet tall, weighing 30 to 40 pounds.SEE ALSO:All The Ways Cops Are Still Trying To Cover Up LaQuan McDonald’s ExecutionOutrageous! Figurines Of White Cherub Crushing Head Of Black Angel Removed From Dollar StoreMeet Jogger Joe, The Man Who Took Racist Cue From BBQ Becky In Tossing Homeless Man’s Clothescenter_img Brittany Bowens , Derion Vence , Maleah Davis A$AP Rocky Being In A Swedish Prison Will Not Stop Her From Going To The Country That Showed Her ‘So Much Love’ There has been speculation from the start that Bowens may have had something to do with her daughter’s disappearance. She said she was “not sure” if there was abuse in her home but Texas Child Protective Services reportedly removed Maleah last year “due to allegations of physical abuse” that “required several surgeries,” ABC reporter Shelley Childers tweeted earlier this month. Although he wouldn’t reveal exactly what Bowens told him, he did say he doesn’t know if she knows where the four-year-old’s body but he did relay everything he knew to the prosecutors, “She knows the truth. She knows eventually she’s going to have to give an answer for that.”Hopefully, she will have to answer sooner than later. Gov. Cuomo Slams Mayor Bill De Blasio For The Eric Garner Case But He Also Failed The Familylast_img read more

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Linda Fairstein Has Another Terminated Contract

first_img Derion Vence, Maleah Davis, Brittany Bowens Entertainment, News and Lifestyle for Black America. News told by us for us. Black America’s #1 News Source: Our News. Our Voice. SUBSCRIBE Thanks for signing up! Get ready for Exclusive content, Interviews,and Breaking news delivered direct to your inbox. Get ready for Exclusive content, Interviews,and Breaking news delivered direct to your inbox. A Disturbing Timeline Of 4-Year-Old Maleah Davis Going Missing After Being Left With Her Stepfather Ava DuVernay‘s “When They See Us” has been universally acclaimed and the title is fitting. The so-called Central Park Five weren’t just five children who had their lives ruined by a racist criminal justice system, they are Kevin Richardson, Raymond Santana, Antron McCray, Yusef Salaam and Korey Wise. However, the miniseries also allowed viewers to see another person — Linda Fairstein. The former Manhattan district attorney prosecutor’s reputation is officially in shambles and now she been dropped by yet another agency.  SEE ALSO:‘It’s Above Me Now’: Hotel Clerk’s Video With Racist Guest Goes Viral‘Who Said I Can’t Say Ni**a?’: Blackface Video Of High School Student Sparks OutrageMeet Jogger Joe, The Man Who Took Racist Cue From BBQ Becky In Tossing Homeless Man’s Clothes A$AP Rocky Being In A Swedish Prison Will Not Stop Her From Going To The Country That Showed Her ‘So Much Love’ Central Park 5 , Linda Fairstein , Manhattan District Attorney’s Office , When They See Us More By NewsOne Staff Meghan McCain Whines That She Can’t Attack llhan Omar Because Trump Is Too Racist See Also: A Timeline Of Dallas Cop Amber Guyger Killing Botham Jean In His Own HomeFairstein was already dropped by her publishing company Dutton. In addition, she has been forced to resign from positions at Vassar College and the non-profit Safe Horizon. Now, her high-powered Hollywood literary agency ICM Partners has also severed ties, according to Deadline. A literary agency is what helps authors land book deals and ICM is one of the most powerful.The news came nearly 24 hours after the 72-year-old defended herself in a vile opinion piece for the Wall Street Journal. Fairstein attacked DuVernay but went even harder on the Black children she helped to throw behind bars. She wrote about them as “rioters” and a “gang of 30” that night in Central Park in April of 1989. She still calls the five men “suspects” who may have not committed the actual rape but, according to her racist delusion, were “acting in concert.”Fairstein did not agree with the charges being dropped even after Matias Reyes confessed. “Nothing Mr. Reyes said exonerated these five of those attacks. And there was certainly more than enough evidence to support those convictions of first-degree assault, robbery, riot and other charges,” Fairstein babbled.She ended her piece with more false claims.“Ms. DuVernay does not define me, and her film does not speak the truth,” Fairstein wrote.Actually, her own behavior defines her and it sounds like she is still trying to control the narrative but it’s not working.In 2002, Kevin Richardson, Raymond Santana, Antron McCray, Yusef Salaam and Korey Wise were exonerated by the New York State Supreme Court.Watch the powerful trailer for “When They See Us” below, which is available on Netflix. Be sure to watch it.  Gov. Cuomo Slams Mayor Bill De Blasio For The Eric Garner Case But He Also Failed The Familylast_img read more

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United States reports new cases of puzzling poliolike disease that strikes children

first_img Sign up for our daily newsletter Get more great content like this delivered right to you! Country Email United States reports new cases of puzzling, poliolike disease that strikes children Country * Afghanistan Aland Islands Albania Algeria Andorra Angola Anguilla Antarctica Antigua and Barbuda Argentina Armenia Aruba Australia Austria Azerbaijan Bahamas Bahrain Bangladesh Barbados Belarus Belgium Belize Benin Bermuda Bhutan Bolivia, Plurinational State of Bonaire, Sint Eustatius and Saba Bosnia and Herzegovina Botswana Bouvet Island Brazil British Indian Ocean Territory Brunei Darussalam Bulgaria Burkina Faso Burundi Cambodia Cameroon Canada Cape Verde Cayman Islands Central African Republic Chad Chile China Christmas Island Cocos (Keeling) Islands Colombia Comoros Congo Congo, the Democratic Republic of the Cook Islands Costa Rica Cote d’Ivoire Croatia Cuba Curaçao Cyprus Czech Republic Denmark Djibouti Dominica Dominican Republic Ecuador Egypt El Salvador Equatorial Guinea Eritrea Estonia Ethiopia Falkland Islands (Malvinas) Faroe Islands Fiji Finland France French Guiana French Polynesia French Southern Territories Gabon Gambia Georgia Germany Ghana Gibraltar Greece Greenland Grenada Guadeloupe Guatemala Guernsey Guinea Guinea-Bissau Guyana Haiti Heard Island and McDonald Islands Holy See (Vatican City State) Honduras Hungary Iceland India Indonesia Iran, Islamic Republic of Iraq Ireland Isle of Man Israel Italy Jamaica Japan Jersey Jordan Kazakhstan Kenya Kiribati Korea, Democratic People’s Republic of Korea, Republic of Kuwait Kyrgyzstan Lao People’s Democratic Republic Latvia Lebanon Lesotho Liberia Libyan Arab Jamahiriya Liechtenstein Lithuania Luxembourg Macao Macedonia, the former Yugoslav Republic of Madagascar Malawi Malaysia Maldives Mali Malta Martinique Mauritania Mauritius Mayotte Mexico Moldova, Republic of Monaco Mongolia Montenegro Montserrat Morocco Mozambique Myanmar Namibia Nauru Nepal Netherlands New Caledonia New Zealand Nicaragua Niger Nigeria Niue Norfolk Island Norway Oman Pakistan Palestine Panama Papua New Guinea Paraguay Peru Philippines Pitcairn Poland Portugal Qatar Reunion Romania Russian Federation Rwanda Saint Barthélemy Saint Helena, Ascension and Tristan da Cunha Saint Kitts and Nevis Saint Lucia Saint Martin (French part) Saint Pierre and Miquelon Saint Vincent and the Grenadines Samoa San Marino Sao Tome and Principe Saudi Arabia Senegal Serbia Seychelles Sierra Leone Singapore Sint Maarten (Dutch part) Slovakia Slovenia Solomon Islands Somalia South Africa South Georgia and the South Sandwich Islands South Sudan Spain Sri Lanka Sudan Suriname Svalbard and Jan Mayen Swaziland Sweden Switzerland Syrian Arab Republic Taiwan Tajikistan Tanzania, United Republic of Thailand Timor-Leste Togo Tokelau Tonga Trinidad and Tobago Tunisia Turkey Turkmenistan Turks and Caicos Islands Tuvalu Uganda Ukraine United Arab Emirates United Kingdom United States Uruguay Uzbekistan Vanuatu Venezuela, Bolivarian Republic of Vietnam Virgin Islands, British Wallis and Futuna Western Sahara Yemen Zambia Zimbabwe Nine-year-old Jayden Broadway from Denver suffered from breathing problems caused by EV-D68 in 2014. The virus may also cause muscle paralysis. Does a virus that usually causes mild cold symptoms sometimes paralyze children? That’s the question facing scientists again this fall, after dozens of previously healthy kids across the United States suddenly lost muscle control in their arms or legs, a condition called acute flaccid myelitis (AFM) that eerily resembles polio.Sixty-two AFM cases in 22 states have been confirmed in recent weeks, scientists at the Centers for Disease Control and Prevention (CDC) in Atlanta said at a news conference today; 65 more are under investigation.Similar waves occurred in 2014 and 2016, and scientists have fingered a relative of the poliovirus, called enterovirus D68 (EV-D68), as a possible culprit. But the evidence isn’t conclusive yet, and it’s unclear why the virus would only paralyze a small minority of children it infects. Solving these mysteries is urgent because the paralysis can be severe and irreversible. AFM is “pretty rare, but it’s pretty devastating,” says Priya Duggal, a genetic epidemiologist at Johns Hopkins Bloomberg School of Public Health in Baltimore, Maryland, who’s studying whether some patients may have a genetic vulnerability to the virus. “And it appears that it’s cyclical. It’s not going away.”center_img By Gretchen VogelOct. 16, 2018 , 4:00 PM Cyrus McCrimmon/GETTY IMAGES Click to view the privacy policy. Required fields are indicated by an asterisk (*) EV-D68, which spreads through saliva and mucus, usually causes symptoms such as coughing, sneezing, and mild fever. It isn’t routinely diagnosed, so no one knows how common it is. But a U.S. outbreak in late summer 2014 was more serious than usual: Hundreds of children hospitalized for severe breathing problems were diagnosed with the virus. Around the same time, more than a dozen children in the Kansas City, Missouri, area and in Denver, which both had large EV-D68 outbreaks, came down with sudden loss of muscle control. Many had mild fever or cough in the days before their symptoms developed, but were otherwise healthy. By December 2014, 120 children in 34 U.S. states had been diagnosed with AFM—“something that hadn’t been reported since the days polio was circulating,” says CDC virologist Mark Pallansch.Scientists suspected a link between the cases of paralysis and the EV-D68 outbreak, but only one patient had evidence of the virus in their cerebrospinal fluid, the usual place to look for pathogens infecting the central nervous system, and fewer than half tested positive in stool or respiratory samples. That may be because samples were taken too late to detect the virus, researchers say; AFM typically appears more than a week after initial cough or fever symptoms.The fall of 2016 saw another wave of the puzzling cases: 149 of them in 39 U.S. states. That year, 29 patients with AFM in 12 European countries tested positive for EV-D68 as well.At today’s press conference, CDC officials did not say whether any of the recent patients have tested positive for enteroviruses, but “the pattern looks very familiar,” says Carlos Pardo-Villamizar, a neurologist at Johns Hopkins University School of Medicine, including the timing: Autumn is known as enterovirus season.Lab research has strengthened the case that EV-D68 could be involved. Last year, Kenneth Tyler of the University of Colorado (CU) School of Medicine in Aurora and his colleagues reported that several strains of EV-D68 could cause paralysis in mice. The virus seemed to target nerve cells involved in muscle control, which makes the link much more plausible, says Kevin Messacar, a pediatric infectious disease specialist also at CU who was not involved in the study. The study also suggests the virus is attacking nerve cells directly, he says, not just triggering an immune response that damages nerves. Others have demonstrated that the virus can infect neuronal cells in the lab. Meanwhile, scientists have found that EV-D68 can be detected much more reliably in respiratory fluids than in cerebrospinal fluid or stool samples, where the poliovirus shows up, which makes identifying infections easier.If EV-D68 is causing paralysis, it’s not clear why it does so in very few cases. But the same is true for the poliovirus, which causes only mild symptoms, or none at all, in more than 99% of those infected. One theory is that the virus can infect nerves in rare cases when it slips into an injured muscle. Another is that genetic factors play a role; Duggal and her colleagues have enrolled nearly 60 families in their study to test that theory.Experts warn that as the 30-year campaign to eradicate polio winds down, attention will shift to other viruses that can paralyze children. (One known example is enterovirus 71; it produces blisters on children’s mouths, hands, and feet, but also occasionally causes AFM.) “We are seeing more cases of this in the U.S. than we are seeing in polio in the whole world,” Tyler says. “You don’t need an awful lot of paralyzed children to make this an important problem.”There is no vaccine against EV-D68. A candidate vaccine developed in China has shown promising results in mice, but at the moment, the rate of serious complications from the virus is probably too low to make widespread vaccination worthwhile, says Heli Harvala, a virologist at University College London. Still, “It might be something we need to consider” in the future, she says. “It’s good to be ready.”Rather than pinning hopes on a vaccine, doctors should be aware of the symptoms of AFM and know how to test for enteroviruses that might be involved, says Thea Kølsen Fischer, a viral epidemiologist at Nordsjællands Hospital in Hillerød, Denmark. “I would rather see investments in surveillance and diagnostics,” which could help front-line clinicians to be ready when the next cluster emerges.last_img read more

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Marilyn Monroe and JFKs Rumored Tryst House Up For Sale

first_imgThe California estate where President John F. Kennedy and Marilyn Monroe are rumored to have had an affair is up for sale for $5 million. Located in Rancho Mirage, just outside of Palm Springs, the Moroccan-themed estate was built for entertainer Bing Crosby in the 1950s and has five bedrooms and five bathrooms spread out over 6,700 square feet, on 1.36 acres of land.It features “expansive and unobstructed views” of Coachella Valley, as well as an array of outdoor gardens, a pool, three fire pits, and an attached casita, according to the site Inside Hook.Photo Courtesy Douglas Elliman Real EstateThe house’s attached two-bedroom casita is rumored to be the place where Marilyn Monroe and JFK would meet in secret.The real estate listing coyly says the house is “fabled to have housed one of our former presidents and his legendary guest, thereby earning its name, the JFK Wing.”The affair between the actress and the president has reached mythic status while not actually having much substantiation.Photo Courtesy Douglas Elliman Real Estate“A passionate love affair between Marilyn Monroe and John F. Kennedy has been assumed for so long that it has achieved as solid a place in public awareness as almost any other event in the man’s presidency,” wrote Donald Spoto, one of Monroe’s more respected biographers.But while the two did know each other, they did not meet often, Spoto said. “All that can be known for certain is that on four occasions between October 1961 and August 1962, the president and the actress met.”JFK with Robert Kennedy and Marilyn Monroe in 1962.One of these four meetings took place at Bing Crosby’s home and it is the time when an affair seems most likely.It was March 24, 1962, and both Monroe and Kennedy were houseguests of Crosby. She told confidante Ralph Roberts afterward “that this night in March was the only time of her ‘affair’ with JFK,” wrote Spoto. Roberts said, “Marilyn gave me the impression that it was not a major event for either of them. It happened once, that weekend, and that was that.”Photo Courtesy Douglas Elliman Real EstateOf course the fourth meeting was when Marilyn Monroe sang to the president at his birthday gala at Madison Square Garden. Afterward, she attended a party for the president, along with many members of his family and his friends, hosted by Arthur and Mathilde Krim.No matter what happened between these two famous figures of the 20th century, the Bing Crosby house was a spectacular home for the “White Christmas” crooner.Marilyn Monroe Happy Birthday Mr. President, 1962. Photo by Cecil Stoughton. White House Photographs. John F. Kennedy Presidential Library and Museum, Boston.Crosby had a number of homes in Palm Springs, including one which President Kennedy visited later on. That visit was also controversial because Kennedy was planning to visit Frank Sinatra, but due to Sinatra’s connections to organized crime, his advisors persuaded him to switch to Crosby.Actor Peter Lawford, Kennedy’s brother-in-law, wrote that when he was told Kennedy would not be his guest, Sinatra was “livid.” He blamed Lawford, and banned him from the Rat Pack.Bing Crosby publicity photo, c. 1930sBing Crosby was neighbors with not only Frank Sinatra but also Ginger Rogers, Kirk Douglas, and Lucille Ball in this exclusive neighborhood.“The home is all about indoor-outdoor living and traditional-meeting-modern design — and it overlooks such a gorgeous backdrop,” realtor Frederik Eklund said in an interview.Photo Courtesy Douglas Elliman Real EstateFortune magazine asked, “What other listing can offer the chance for caroling around a pool and fire pit with such a level of celebrity history? The house is in decent shape but could use some upgrades.”“Along with a well-proportioned main structure with retractable glass walls, the purchase includes an adjacent half-acre lot on which owners can build a small guest house for future presidential affairs.”Palm Springs had a special status among celebrities in the 1950s and 1960s.Read another story from us: Art Deco House with Original Vintage Furnishings For Sale – Take a Tour“Without Hollywood, it can be argued, there would be no Palm Springs as we know it today,” wrote Howard Johns in his book Palm Springs Confidential.last_img read more

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West Coast Credit Union launches its 2019 Summer School Programme

first_imgShareTweetSharePinIn view of the universal Credit Union’s education philosophy, the West Coast Cooperative Credit Union, on Monday June 3rd , launched its 2019 Summer School Programme.The initiative was born out of the society’s assessment of the needs of the communities it serves and is driven by the staff of the institution.The programme was crafted for minors and children of members of the society between the ages of 5 and 12 and aims to nurture, train, educate and entertain.WCCCU Summer School Programme runs from July 15th to July 26th at the Coulibistrie Primary School. Transportation will be provided for students from the communities of St. Joseph, Salisbury and Colihaut, who wish to attend.The two week-long summer activity will consist of themed days, like (Crazy Hair Day), fun art, field trips, outdoor games, a Co-operative Day, educational discussions and Math and Reading.  It will culminate with a certificate and prize-giving ceremony, and a Fantastic Fun Day.   Registration can be done at any of the WCCCU branch offices from June 3rd, 2019.West Coast prides itself in being able to give back to the communities it serves in such a practical manner.  The Board and management express appreciation to fellow members, serving volunteers, staff and well-wishers who contribute and work toward the continued success of the Society.last_img read more

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Men get larger first NIH grants but is the news all bad

first_imgGary Waters/Getty Images Country * Afghanistan Aland Islands Albania Algeria Andorra Angola Anguilla Antarctica Antigua and Barbuda Argentina Armenia Aruba Australia Austria Azerbaijan Bahamas Bahrain Bangladesh Barbados Belarus Belgium Belize Benin Bermuda Bhutan Bolivia, Plurinational State of Bonaire, Sint Eustatius and Saba Bosnia and Herzegovina Botswana Bouvet Island Brazil British Indian Ocean Territory Brunei Darussalam Bulgaria Burkina Faso Burundi Cambodia Cameroon Canada Cape Verde Cayman Islands Central African Republic Chad Chile China Christmas Island Cocos (Keeling) Islands Colombia Comoros Congo Congo, the Democratic Republic of the Cook Islands Costa Rica Cote d’Ivoire Croatia Cuba Curaçao Cyprus Czech Republic Denmark Djibouti Dominica Dominican Republic Ecuador Egypt El Salvador Equatorial Guinea Eritrea Estonia Ethiopia Falkland Islands (Malvinas) Faroe Islands Fiji Finland France French Guiana French Polynesia French Southern Territories Gabon Gambia Georgia Germany Ghana Gibraltar Greece Greenland Grenada Guadeloupe Guatemala Guernsey Guinea Guinea-Bissau Guyana Haiti Heard Island and McDonald Islands Holy See (Vatican City State) Honduras Hungary Iceland India Indonesia Iran, Islamic Republic of Iraq Ireland Isle of Man Israel Italy Jamaica Japan Jersey Jordan Kazakhstan Kenya Kiribati Korea, Democratic People’s Republic of Korea, Republic of Kuwait Kyrgyzstan Lao People’s Democratic Republic Latvia Lebanon Lesotho Liberia Libyan Arab Jamahiriya Liechtenstein Lithuania Luxembourg Macao Macedonia, the former Yugoslav Republic of Madagascar Malawi Malaysia Maldives Mali Malta Martinique Mauritania Mauritius Mayotte Mexico Moldova, Republic of Monaco Mongolia Montenegro Montserrat Morocco Mozambique Myanmar Namibia Nauru Nepal Netherlands New Caledonia New Zealand Nicaragua Niger Nigeria Niue Norfolk Island Norway Oman Pakistan Palestine Panama Papua New Guinea Paraguay Peru Philippines Pitcairn Poland Portugal Qatar Reunion Romania Russian Federation Rwanda Saint Barthélemy Saint Helena, Ascension and Tristan da Cunha Saint Kitts and Nevis Saint Lucia Saint Martin (French part) Saint Pierre and Miquelon Saint Vincent and the Grenadines Samoa San Marino Sao Tome and Principe Saudi Arabia Senegal Serbia Seychelles Sierra Leone Singapore Sint Maarten (Dutch part) Slovakia Slovenia Solomon Islands Somalia South Africa South Georgia and the South Sandwich Islands South Sudan Spain Sri Lanka Sudan Suriname Svalbard and Jan Mayen Swaziland Sweden Switzerland Syrian Arab Republic Taiwan Tajikistan Tanzania, United Republic of Thailand Timor-Leste Togo Tokelau Tonga Trinidad and Tobago Tunisia Turkey Turkmenistan Turks and Caicos Islands Tuvalu Uganda Ukraine United Arab Emirates United Kingdom United States Uruguay Uzbekistan Vanuatu Venezuela, Bolivarian Republic of Vietnam Virgin Islands, British Wallis and Futuna Western Sahara Yemen Zambia Zimbabwe By Jocelyn KaiserMar. 8, 2019 , 9:45 AM Click to view the privacy policy. Required fields are indicated by an asterisk (*) Men get larger first NIH grants, but is the news all bad for female scientists? Sign up for our daily newsletter Get more great content like this delivered right to you! Country But lost in the tweets and widespread press coverage—and buried in the paper—was a nugget of good news: For first-time R01s, NIH’s main independent research project grant, women received a median of $364,509—5% more than men. NIH has also long found that for all (not just first-time) R01s, women got larger awards, but men have more awards overall and therefore more total funding.What’s more, the agency’s latest data show modest differences between men and women in a broader category of funding called research project grants (RPGs) that includes R01s and is defined as support for specific projects performed by a named investigator. RPGs are often crucial for sustaining a lab and gaining tenure. In 2018, women’s overall RPG awards averaged $519,000, or 5% less than men. (At the National Institute of General Medical Sciences [NIGMS], one of NIH’s 27 institutes, analyses have found minimal gender differences for that institute’s RPGs. However, as with all NIH R01s, men held more grants overall.)So why did the Northwestern authors find a much larger disparity of 24% in median award size? The explanation seems to be that the team looked at all 225 NIH award types—from small awards for training and conferences to large center grants, which support multiple projects, and contracts that often fund research services or resources, such as creating reagents or coordinating clinical trial data. The median awards to men were substantially higher in some non-RPG categories: In particular, male PIs got $126,000 more for a contract called an N01 that accounted for almost one-third of all funding examined.Jeremy Berg, a former NIGMS director who is now editor-in-chief of Science, calls the study “sloppy” because it “mixes apples and oranges.” He also finds it confusing that an investigator’s first award could be a center grant, which almost always go to experienced researchers with previous grants. “Overall, I think this provides more heat than light and is essentially useless in terms of thinking about policy implications,” Berg says.But Brian Uzzi, a co-author on the JAMA paper with postdocs Diego Oliveira and Yifang Ma, defends his team’s decision to cast a wide net and study a range of funding categories besides R01s and other RPGs. The R01s made up only 11% of all NIH grant money in the study, he notes. And, he adds, even if it’s for a resource or a conference, “any grant money is advantageous for an individual’s career.” Email A headline-grabbing study out this week is adding to concerns about gender bias in science: Women received about $40,000 less than men in their first funding award from the National Institutes of Health (NIH), or just $127,000 per year. But surprisingly, women’s median award size was larger than men’s for NIH’s standard independent research grant. A close look at the data, which cover more than 200 different kinds of grants awarded by NIH, suggests the story is more nuanced than the overall numbers indicate.Researchers at Northwestern University in Evanston, Illinois, examined 53,903 grants from 2006 to 2017 that went to first-time principal investigators (PIs). Men and women didn’t differ significantly in some research metrics, such as the number of publications. Yet the median size of a grant for male PIs was $165,721, whereas for women it was just $126,615 or 24% smaller, the authors reported on 5 March in JAMA. The results were even more striking for some types of institutions: At Big Ten public universities, for example, grants to men were more than twice as large as those to women ($148,076 versus $66,365).That difference has profound implications for a woman’s scientific career, the study’s authors say. “This shows women are disadvantaged from the very first NIH grant they submit relative to their male counterparts. This represents an early stumbling block” that means women have less money for equipment and hiring graduate students, corresponding author Teresa Woodruff wrote in a press release. NIH, too, “is aware and concerned about differences in funding patterns between women and men in science,” the Bethesda, Maryland–based agency wrote in a statement.last_img read more

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CES 2018 Artificial Intelligence at Home and Behind the Wheel

first_imgPanasonic announced a series of new efforts to expand its connected car technology, including working with Alexa to provide voice assistant technology for its Panasonic Skip Generation Platform in connected cars.For example, customers will be able to use simple voice commands to prompt Alexa to play music from streaming services, to provide directions to local venues like coffee shops, to make sure the house is locked and lights are turned off, or to order a pizza delivery on the way home.Panasonic and Qualcomm originally announced the technology at last year’s CES. It allows OEMs to create a seamless in-vehicle entertainment experience based on Android 7.0 and the Snapdragon 820Am processor.Toyota made a huge splash with its autonomous vehicle technology. The company announced a new business alliance and concept vehicle called “e-Palette,” which will function as a platform for creating self-driving vehicles designed for everything from food and package delivery to medical transportation to ride-sharing in big cities.Company president Akio Toyoda announced the new program at CES and introduced initial launch partners — Amazon, DiDi, Mazda, Pizza Hut and Uber — that will work on planning, application concepts and vehicle verification.The plan calls for the vehicles to use next-generation electric batteries. They will come in three different sizes, and companies will be able to install their own automated driving systems and vehicle management technology.Pizza Hut, for example, plans to use the vehicles to help with deliveries, noted spokesperson Doug Terfehr.Also under consideration is development of a mobile kitchen so pies could be made on the road, he told TechNewsWorld.”Toyota’s announcement underscores merely what’s been going on [in the industry], from pilot delivery to automated ride-sharing and car-related services,” Matt DeLorenzo, managing editor at Kelley Blue Book, told TechNewsWorld.Toyota plans to begin testing the vehicles by 2020 in the U.S. and other locations, and it intends to deploy the cars at the 2020 Olympics and Paralympic games. Smart Cars David Jones is a freelance writer based in Essex County, New Jersey. He has written for Reuters, Bloomberg, Crain’s New York Business and The New York Times. Making New Inroads Artificial intelligence dominated CES 2018 in a big way on Monday with major announcements on connected car advances and home system technologies. Google all but declared war on Amazon with its Google Assistant voice technology making its presence known at nearly every turn on the showroom floor.LG rolled out a new lineup of high-end AI OLED and Super UHD televisions infused with its ThinQ AI technology and Alpha 9 technology, combining cinema-quality home entertainment with the ability to voice control the entire home.The ThinQ technology, which integrates LG’s WebOS smart TV platform with Google Assistant, will allow customers to use hundreds of voice commands to search for specific content, control various functions on the television, and control home appliances.LG introduced a total of nine new 4K AI OLED televisions, ranging from 55 to 77 inches, and seven new AI UHD televisions ranging from 55 to 75 inches. center_img Those on hand for one of the most anticipated events at CES were disappointed. The demonstration of Workhorse Group’s SureFly, the first approved electric hybrid helicopter in the world, was postponed due to bad weather in the Nevada location where the autonomous vehicle was scheduled for a demonstration run.The FAA just recently approved an Experimental Airworthiness Certificate allowing test flights of the two-person, self-propelled copter, noted spokesperson Mike Dektas, and a demonstration with passengers had been set to take place Monday afternoon. Google and LG have expanded their collaboration — which started with mobile phones — to include watches, OLED TVs, refrigerators, washing machines, ovens and other products, Scott Huffman, vice president of engineering for Google Assistant, told CES attendees.The two companies also have been collaborating on a smart speaker scheduled to launch later this year.”Google is here in a big way to promote its solutions and combat Amazon,” said Jim McGregor, principal analyst at Tirias Research.Amazon’s Alexa has been winning most of the initial battles for new business, he told TechNewsWorld, but vendors have been supporting both platforms.In terms of the global market, Google has an opportunity to make inroads in markets where Amazon does not compete on the same level, noted Marc Beccue, principal analyst at Tractica.”Why? Biggest span of languages covered and legacy market penetration from Android and Chrome,” he told TechNewsWorld. “Amazon is more limited in language capabilities and legacy market penetration for Amazon.com.”While Amazon was noticeably missing from the show in terms of booth presence, the company’s technology did manage to find its way into some fairly significant new product announcements. Rained Outlast_img read more

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Google Hasnt Kept Promise to Stop BubbleWrapping Users Report

first_imgSearch results can change over time, with the inclusion of time-sensitive links, for example. That factor was controlled for by having everyone search at the same time.Location can impact search results — by including local news articles, for example. To control for that, DuckDuckGo manually checked all links, comparing them to the volunteer’s city and state, and replacing all of them with the same placeholder — “localdomain.com” for organic links and “local source” for infoboxes.So, if two users’ results differed only by a different local domain in the same slot, that would not count as different. However, the adjustment did not significantly affect overall variation, DuckDuckGo found.The study’s methodology and conclusions are flawed, because they are based on the assumption that any difference in search results is based on personalization, which is not true, Google told 9to5Google.Time and location are among the factors that can lead to slight differences, and the DuckDuckGo study does not appear to have controlled for those two factors effectively, Google argued.”The study seems to account for time and location fairly well by [using] a common domain,” Constellation’s Wang said. DuckDuckGo “did a reasonable job.” Most people saw results customized for them.In private browsing mode, logged out, a search for “gun control” resulted in 62 variations, and 52 of 76 participants saw unique results. In normal mode, 58 variations were served up, and 45 of the 76 participants saw unique results; In private browsing mode, logged out, a search for “immigration” resulted in 57 variations, with 43 of 76 participants seeing unique results. In normal mode, there were nine variations, with unique results for 48 of 76 participants; In private browsing mode, logged out, a search for “vaccinations” returned 73 variations, with unique results for 70 of 76 participants. In normal mode, there were 73 variations, with 70 of 76 participants seeing unique results. Questions of Time and Place For DuckDuckGo’s study, 87 volunteers across the United States searched Google on June 24, 2018, at 9 p.m. ET, using identical search terms.Seventy-six of them used desktops and the remaining 11 used mobile devices.They first searched in private browsing (incognito) mode while logged out of Google, then in normal mode.The data is available for download in two parts: basic non-identifiable participant data, and raw data from the search results.The code DuckDuckGo wrote to analyze the data is open source and available on its GitHub repository. Bing rolls social results into its search results. Amazon uses Bing for its FireOS devices, and its own A9 search engine for products.DuckDuckGo focused on Google because “Google is the monopoly provider for search by a landslide, with over 90 percent market share worldwide, and more than 95 percent in many countries,” said DuckDuckGo Community Manager Daniel Davis.”As such, we focused on them to start, though we would love to see further research in this area,” he told TechNewsWorld.Although DuckDuckGo is a Google competitor, “their arguments stand scrutiny,” said Jon von Tetzchner, CEO of Vivaldi.”Anyone that does a search comparison will see that for themselves,” he told TechNewsWorld.Vivaldi earlier this year became the first browser to enable DuckDuckGo as the default search engine in its Private Windows. The problem is “particularly pernicious when searching for political topics,” Davis said.If undecided voters get biased information when conducting research on political topics, the search engine manipulation effect can shift the voting preferences of undecided voters by at least 20 percent.”The issue with filter bubbles is that we live in an echo chamber, which means we only see, hear and act on what we prefer to,” observed Ray Wang, principal analyst at Constellation Research.”We never address the hard issues,” he told TechNewsWorld.The tradeoff is personalization and convenience, Wang said.”Most folks want things tailored and customized to their needs. Advertisers want to make money on clicks. So it continues.” Participants did not see the same results in private browsing mode. When randomly comparing people’s private modes to each other, there was more than double the variation than when comparing the private mode and normal mode results for the same individual, DuckDuckGo noted.This shows that Google tailors search results regardless of browsing mode, DuckDuckGo warned.However, “there is a slight possibility that the algorithm may be doing this and Google has not accounted for unintentional bias,” Wang suggested.”I believe Google is trying to provide the best possible search results, and that this is an unintended consequence of that work,” Vivaldi’s von Tetzchner said. DuckDuckGo’s Methods Privacy? What Privacy? Different Strokes for Different Folks – click image to enlarge – – click image to enlarge – Google hasn’t released consumers from its filter bubble — the package of personalized search results it delivers — despite having promised to do so, according to study results DuckDuckGo released Tuesday.DuckDuckGo’s findings:Most participants saw results unique to them, which could not be explained by changes in location, time, by being logged into Google, or by Google testing algorithm changes with a small subset of users; On the first page of search results, Google included links for some participants that it did not include for others, even when logged out and in private browsing mode; Results within the news and videos in-boxes varied significantly. Participants were shown different sources, even after accounting for location; and Private browsing mode and being logged out of Google offered very little filter bubble protection. DuckDuckGo looked only at websites’ top-level domains.To count variants of results, DuckDuckGo noted the order of the major elements: the organic (regular) links, the news (top stories) infobox, and the videos infobox. It ignored ads, sections containing related searches, and other infoboxes.Results from mobile devices were excluded when variations were counted because there can be significant variations in the number of infoboxes displayed by mobile and desktop devices.Google search results typically have 10 organic links, but, in private browsing mode, logged out of Google and with local domains replaced with “localdomain.com,” DuckDuckGo found the following:”Gun Control”: 19 different domains; “Immigration”: 15 different domains; and “Vaccinations”: 22 different domains. “Some people were shown a very unusual set of results relative to the other participants — offered some domains seen by no one else,” DuckDuckGo’s Davis said.”If you were one of these people, you would have no way of knowing what you’re missing,” he pointed out. Possible Solutions Google “should offer an unfiltered and unbiased search results page that is easily accessible, such as when logged out, in incognito mode, or with the ‘Do Not Track’ browser setting turned on,” DuckDuckGo’s Davis suggested. “We currently offer such unfiltered search results for all users regardless of their browser configuration.”Collecting data helps Google show consumers targeted ads, but “we show advertising based on individual search terms,” Davis noted. “We’ve been profitable since 2014, and it’s possible to thrive as a business without collecting or storing personal data.”Consumers should “use non-Google products” and reduce their digital footprint as much as possible, he suggested.”I use mostly Firefox and DuckDuckGo because of the privacy aspects,” Constellation’s Wang said.Search engines should provide an “absolute” mode, he suggested, which is “what everyone sees instead of what your customized mode may look like.” Richard Adhikari has been an ECT News Network reporter since 2008. His areas of focus include cybersecurity, mobile technologies, CRM, databases, software development, mainframe and mid-range computing, and application development. He has written and edited for numerous publications, including Information Week and Computerworld. He is the author of two books on client/server technology. Email Richard.last_img read more

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Newly developed synthetic DNA molecule may one day be used as vaccine

first_imgReviewed by James Ives, M.Psych. (Editor)Oct 19 2018Researchers from City of Hope, a world-renowned comprehensive cancer center and independent biomedical research institution, have developed a synthetic DNA molecule that is programmed to jump-start the immune system to eradicate genetically distinct types of prostate cancer.Their novel two-step strategy eliminates STAT3, a master key that enables tumors to become resistant to existing therapies, and toll-like receptor 9 (TLR9), a danger sensor present but not effectively active in immune system cells such as dendritic cells. The short DNA programmed by City of Hope researchers temporarily lifted the defense shield of tumors and awakened the immune system in human cell and mouse models to eradicate difficult-to-treat prostate cancers.Related StoriesUsing machine learning algorithm to accurately diagnose breast cancerScripps CHAVD wins $129 million NIH grant to advance new HIV vaccine approachNew protein target for deadly ovarian cancer”We desperately need new strategies for late-stage prostate cancers, which thus far have resisted emerging immunotherapies,” saidThe preclinical study, published on Oct. 18 in the journal Clinical Cancer Research, created a blueprint of a new type of DNA or “oligonucleotide” drug – CpG-STAT3ASO. It is programmed with two functions to more effectively and safely treat metastatic cancers that are resistant to pharmacological therapies. Notably, using a synthetic molecule with just STAT3 or TLR9 was not as effective in killing prostate cancer as using the two in unison, the study found.”While existing immunotherapy options can improve outcomes for selected prostate cancer patients, it is clear that these patients are in the minority,” saidIt is too early to know, Kortylewski said, but it’s possible that this DNA molecule could be used in the future for therapeutic vaccination against metastatic prostate cancer. Such an agnostic and off-the-shelf approach could work regardless of the genetics of an individual’s prostate cancer. But more preclinical research on the pharmacologic properties of these new drugs is needed to get there, he said.Dayson Moreira, Ph.D., a staff scientist in the Department of Immuno-Oncology at City of Hope, is the first author of the study. Researchers at the University of Notre Dame and the University of Texas MD Anderson Cancer Center also contributed to the study.Some of the authors have ownership interests, including patents, or have a role as a consultant or advisory board member at pharmaceutical companies. Kortylewski has a patent on STAT3 inhibitors and their uses. Source:https://www.cityofhope.org/last_img read more

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